Since I don't think there's a hidden gems thread for these I'll mention it here:
Dropout TV:
The Hank Green stand-up special, Pissing Out Cancer, is really, really good. It's very funny, insightful and moving.
I also finally got around to the two-part season finale of Game Changer and it's amazing. So many funny parts from all involved. Then I watched the behind the scenes and it's amazing how much went into putting it together.
Nebula:
IDENTITEAZE- a short film / sci-fi thriller that's very good and worth watching. Staring Maggie Mae Fish, James Tison and featuring John de Lancie.
Cool new research, published in Nature a few months ago, describes one mechanism for the brain removing amyloid (a brain waste product that forms plaques in people with Alzheimer's).
https://www.npr.org/sections/shots-h...
Kipnis and his team began looking at what the brain was doing as it slept. As part of that effort, they measured the power of a slow electrical wave that appears during deep sleep in animals.
And they realized something: "By measuring the wave, we are also measuring the flow of interstitial fluid," the liquid found in the spaces around cells, Kipnis says.
It turned out that the waves were acting as a signal, synchronizing the activity of neurons and transforming them into tiny pumps that push fluid toward the brain's surface, the team reported in February in the journal Nature.
A comment on this study suggested that an external source of synchronizing waves might be used to help patients whose brains have difficulty removing waste, as was used in research with mice: "It really makes me wonder about some of the things humans do with sound -- singing bowls, sound baths, didgeridoos, trance."
I got a new backpack for my birthday this year. I have been drooling over it for about 10 years. Just going back to look at it again ever so often, thinking, one day I'll get one of these... WELL, this year, I told my family it was the only thing I wanted, so it could be gift from multiple folks, since they are pretty pricey.
I LOVE it, can't WAIT to really get to use it in our travels.
I can't 100% vouch for it yet, as I have only really used it to carry some groceries back from the store... but it LOOKS like it is truly going to fit perfectly into the use case I wanted. So, if you are looking for a backpack, specifically for travel, as this one is designed to be exactly carry on size, this one is worth a look.
Cool new research, published in Nature a few months ago, describes one mechanism for the brain removing amyloid (a brain waste product that forms plaques in people with Alzheimer's).
I wonder if it can help with senility in general. At least to the point that we can grow new cells to replace the removed ones...
DIE PRIONS! (in mice)
https://www.nature.com/articles/d415...
A molecular-editing tool that’s small enough to be delivered to the brain shuts down the production of proteins that cause prion diseases, a rare but deadly group of neurodegenerative disorders.
The system — known as coupled histone tail for autoinhibition release of methyltransferase (CHARM) — changes the ‘epigenome’, a collection of chemical tags that are attached to DNA and affect gene activity. In mice, CHARM silenced the gene that produces the harmful proteins that cause prion disease in most neurons across the brain without altering the gene sequence.
CHARM is the first step towards developing a safe and effective ‘one and done’ treatment for reducing the levels of the disease-causing proteins, says Madelynn Whittaker, a bioengineer at the University of Pennsylvania in Philadelphia. The findings were published [Jun 27 2024] in Science.
Andy Goldsworthy is a British sculptor, renowned in his field, that creates temporary landscape art installations out of sticks and stones, and anything and everything else that he finds outside.
Andy Goldsworthy’s work is so stunning.
I'm glad they plead guilty, but that doesn't look like much of an actual win, which I suppose is why they agreed to it. That ~1/2 billion dollar fine is only a fraction of what they make in a single year. Plus the whole reason they were sued in the first place was for violating an existing legal requirement to improve safety procedures, so a new requirement for them to improve safety procedures doesn't seem like much of an actual punishment since they were already supposed to be doing that anyways.
I'm glad they plead guilty, but that doesn't look like much of an actual win,
What would "an actual win" have looked like to you?
Jail the management / C-Suite team that was responsible for putting profits ahead of safety. From what I gather (and I am not even close to being an expert) they used the wrong management team after the merger. This is not even a slap on the wrist - hell, they even get to have a say in who gets to monitor their adherence to the new requirements put in place by the DoJ.
Yeah, some actual legal repercussions for the people that made these decisions and a *much* larger fine, to start. An admission of Boeing's fault/guilt for the crashes that the families of those that died can use in civil suits would be more than appropriate too.
Jail the management / C-Suite team that was responsible for putting profits ahead of safety.
Buddy, you're mad at CAPITALISM, not at Boeing.
Yeah, some actual legal repercussions for the people that made these decisions and a *much* larger fine, to start. An admission of Boeing's fault/guilt for the crashes that the families of those that died can use in civil suits would be more than appropriate too.
The fine was the largest possible fine allowable under the law. So there is no larger fine that can be applied. You got what you wanted there.
The admission of guilt is right there in the headline. So you got what you wanted there too.
Rallick wrote:Jail the management / C-Suite team that was responsible for putting profits ahead of safety.
Buddy, you're mad at CAPITALISM, not at Boeing.
You can be mad at more than one thing at a time. Don't let defeatism prevent you from wanting justice
Rallick wrote:Jail the management / C-Suite team that was responsible for putting profits ahead of safety.
Buddy, you're mad at CAPITALISM, not at Boeing.
Stengah wrote:Yeah, some actual legal repercussions for the people that made these decisions and a *much* larger fine, to start. An admission of Boeing's fault/guilt for the crashes that the families of those that died can use in civil suits would be more than appropriate too.
The fine was the largest possible fine allowable under the law. So there is no larger fine that can be applied. You got what you wanted there.
The admission of guilt is right there in the headline. So you got what you wanted there too.
I realize you used to work for Boeing and might possibly still feel a bit of loyalty, but come on. Those arguments are ridiculous.
The fine being the maximum just means the law limiting it is broken, it doesn't mean it is an appropriate punishment. As long as the maximum fine imposable by law is less than the expected profits for violating the law, the law is useless and the fines are just seen as the cost of doing business.
Their guilty plea was only for violating the 2021 differed prosecution agreement. It does not mean they're admitting fault for the crashes.
Rallick wrote:Jail the management / C-Suite team that was responsible for putting profits ahead of safety.
Buddy, you're mad at CAPITALISM, not at Boeing.
I mean, yes, I am mad at capitalism, too. But I'm definitely mad at those assholes who put profits so far ahead that literally hundreds of people got killed. And not one of them will see any personal repercussions. Yes, that definitely pisses me off.
Buddy, you're mad at CAPITALISM, not at Boeing.
One can easily be mad at both. Boeing decided to replace their leaders, which were engineers, with finance guys, and this is what happened.
Yes, there should absolutely be more penalties than we got but I’m glad to see anything. Jail time should easily be on the table.
I realize you used to work for Boeing and might possibly still feel a bit of loyalty,
Just to nip this in the bud, I have zero loyalty to Boeing, am not shilling for them, and no interest in their continuing success or not. What I do have is an appreciation for the enormous amount of nuance and complexity in the process of building and certifying airplanes, which is often entirely absent from these kinds of conversations.
Not to pick on Veloxi, but posts like the following are a good poster child for what I'm talking about, a narrative based on a grain of truth that so oversimplified that it's useless.
One can easily be mad at both. Boeing decided to replace their leaders, which were engineers, with finance guys, and this is what happened.
That was 30 years ago. So much water has passed under the bridge since then. That may have been in inciting event, but it's so far down the causal chain that it's barely relevant to what's happening today.
Stengah wrote:I realize you used to work for Boeing and might possibly still feel a bit of loyalty,
Just to nip this in the bud, I have zero loyalty to Boeing, am not shilling for them, and no interest in their continuing success or not. What I do have is an appreciation for the enormous amount of nuance and complexity in the process of building and certifying airplanes, which is often entirely absent from these kinds of conversations.
How does having that appreciation lead you to decide to argue that because the law prevented the fine from being higher that it rightly shouldn't have been higher? Or falsely asserting that an admission of guilt in violating the deferred prosecution agreement was the equivalent of admitting fault in the crashes?
It doesn't really sound like Veloxi's the one spinning a narrative based on a grain of truth that is so oversimplified that it's useless.
I love it when people take bickering in the love thread to a D&D thread
"Fiduciary responsibility" is the new, "I was just following orders."
"Fiduciary responsibility" is the new, "I was just following orders."
That was 30 years ago. So much water has passed under the bridge since then. That may have been in inciting event, but it's so far down the causal chain that it's barely relevant to what's happening today.
Yeah, forget about that first domino falling thirty years ago. It's all water under the bridge now.
Give me a god damned break.
Just to be clear, fiduciary responsibility is a neutral term. It refers to someone who has a legal responsibility to act in someone else's financial interests. What I think is meant here is the form that is usually stated as "maximizing shareholder value", and of course that is not a legal requirement for companies in the US, so calling it fiduciary responsibility is wrong. It's nothing of the sort.
The reason that matters is that there are a relatively small number of companies that are actually SEC certified as fiduciaries, which provide financial advice and management services that are *legally required* to be in the interest of the customer. When you need financial advice, you want to run *towards* a Fiduciary, not away, because they are the best of a business that is otherwise fraught with people trying to take your money.
Fine, "I was just maximizing shareholder value" is the new "I was just following orders."
Literally true. 
The flat earth community is in chaos right now because someone has organized a trip to Antarctica to view the 24-hour sun- something impossible according to flat earthers, who also largely think it’s impossible to go to Antarctica at all in the first place. A couple flat earthers have agreed to go on this trip and now every other flerfer is attacking them as plants/dupes, or trying to convince them it’s a trap, or trying to pre-debunk the inevitable results of this “final experiment” trip, and it’s just an endless amount of hilarious free entertainment for the rest of us “globeheads.”
The flat earth community is in chaos
I thought the flat earth community was more people being ironically skeptical than folks who actually believe the earth is flat. I guess stupidity has no lower limit.
ruhk wrote:The flat earth community is in chaos
I thought the flat earth community was more people being ironically skeptical than folks who actually believe the earth is flat. I guess stupidity has no lower limit.
Sadly no. For a while the largest flat earth group was a satirical one but the age of social media brought a resurgence of actual flat earth believers in the early/mid 2010’s. The movement has sort of plateaued currently but the community is still a lot larger now than it was in the pre-social media days.
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