Gray Matter is the latest release from Jane Jensen, adventure game designer extraordinare. She co-designed King's Quest VI with Roberta Williams (by far the best KQ game in the series), then went on to create Gabriel Knight I-III, one of the best trilogies ever penned. Suffice it to say, she knows her stuff.
Gray Matter had a long, troubled path up to release, going through two developers and two publishers before finally coming out something like seven years after the start of development. But here we are. Stateside release is Feb. 22nd. Supposedly it's a pretty classic adventure game, with all the rich depth of story that we've come to expect from Jensen; but it isn't without its warts. Metacritic scores have been mostly positive so far (it's already out in Europe), with no score below a 70 with the exception of Edge Magazine (big surprise there). It's mostly getting very high marks for story and focus, and dinged for more technical issues like character animation. Pretty much exactly what I would expect from Jensen.
By the way, "makers" is plural because her second husband, Robert Holmes -- who wrote the score for all three GK games -- wrote the score for Gray Matter as well.