Recommend me some fun St. Louis nightclubs or bars.

So, I'm taking the wife and some friends to St. Louis for a hockey game in a couple weeks and I'm trying to decide where we're going to go the night before and after.

We're not really looking for anything in particular, just some places with good drinks, good music and a more mature crowd. Ideally we'd like to have a few places near each other that we could choose from. I'd also like to get a decent hotel room nearby so we could avoid cabs...

Pretty demanding I know, but really I'm just looking for someone to tell me what area of town I should be targeting.