Not sequels, not remakes, but new ideas or games based on other media that haven't been done yet.
Me? I'd like to see a game based on The Flash, preferably done by the guys who did Hulk: Ultimate Destruction. Something along the lines of that combined with the gameplay in Ultimate Spiderman/Spiderman 2 - and of course, with Bruce Campbell narrating as in Spiderman 2 as well. I can easily imagine this on the 360.