Yes the people adapting it suck, but still, I can't help but be bouncing off the ceiling at this news. Seriously the best comic series of all time by a wide wide margin.
Jesse Custer: Nathan Fillion
Cassidy: Robert Carlyle
Tulip: Katee Sackhoff (though I know she couldn't do two shows at once)
Herr Star: Stellan SkarsgÃ¥rd or go nuts and get Clancy Brown (assuming he can do a decent german accent)