When my brother and I lived together we got a cat and named her Tilley. She has never been super affectionate or anything (I think it has something to do with her breed) but she never attacked people outside of the usual cat playing kind of stuff.
Well, a couple years ago my brother and I went our separate ways and he kept Tilley. My brother moved into a small one bedroom apartment and slowly Tilley seemed to get more and more aggressive. It was mostly when he would have a girl over, Tilley would attack her and generally not be very nice. After over a year or this it got to the point where she didn't like being petted, she only let myself or my brother pick her up and she got more aggressive. I should also mention that she developed strange eating habits, she would gorge on any food put down for her. If you gave her a bowl of dry food she would eat it all without even really chewing it and eventually toss it up again. Once that started happening my brother started feeding her wet food twice a day instead.
Well, things have come to a head recently. About a month ago my brother moved into a house with a couple other people and Tilley has gone nuts. She is attacking his room mates, blocking their way down hall ways and so far she has done some serious damage to their arms. My bro took her to the vet and she checked out fine so we don't think she is ill in that sense. After consulting with the vet the members of the house has tried things like making noise when she attacked people (a pepsi bottle full of pennies or whatever) but that hasn't helped at all. About a week ago they put Tilley on some anti-depressants for cats that were supposed to mellow her out and make the training a bit easier. Instead, she sleeps more but she continues to attack people. In fact, just today my brother picked her up to put her outside (they have a small fenced in back yard) and she tore his arms up pretty good.
He is running out of options. She doesn't do well with other animals and she isn't an outdoor cat at all. I doubt she would be very welcome at a farm somewhere because of that. Trying to curb her behaviour isn't working so far and they are running out of ideas.
Tilley is four years old, we would both hate to have her put down but we're afraid there may not be any other option. What do you guys think?