Which patches do I need to get Fallout 1 working?

So I recently bought the Falllout Collection CD for a song and I've been trying to figure out which mods and patches I should install to get the best game experience on a first playthrough. So far I've installed the high-resolution patch from No Mutants, but if you do a search you will find a lot of different patches and mods.

Which ones do I actually want to install and which ones are unnecessary? Thanks!